MMT for Inclusion Body Myositis; Muscle Study Group 2001 (MMT IBM MSG 2001)
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General Information
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| Objectives |
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This is a manual muscle test as used for two inclusion body myositis trials conducted by the Muscle Study Group published in 2001 and 2004.
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| Category of Outcome Measure |
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| Chronology of Development |
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This was used in IBM trials conducted by the Muscle Study Group published 2001 and 2004. It is identical that that published Brooke et al 1981 for Duchenne Muscular Dystrophy studies (see MMT DMD Brooke 1981).
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| Mode of Assessment |
Administered by trained evaluator
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| Age Group |
Adults (16 Years and Over)
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| Conditions of Use and Contact Information |
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Manual Muscle Testing
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| Total Number of Muscles Tested (Unilateral) |
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| Total Number of Muscles Tested (Bilateral) |
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| Actual Muscles Tested |
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Proximal |
Distal |
Not Defined |
| Neck Flexion |
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X |
| Neck Extension |
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X |
| Shoulder Abduction |
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X |
| Shoulder External Rotation |
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X |
| Elbow Flexion |
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X |
| Elbow Extension |
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X |
| Wrist Flexion |
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X |
| Wrist Extension |
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X |
| Thumb Abduction |
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X |
| Hip Extension |
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X |
| Hip Flexion |
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X |
| Hip Abduction |
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X |
| Knee Flexion |
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X |
| Knee Extension |
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X |
| Ankle Dorsi Flexion/Tibialis Anterior |
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X |
| Ankle Plantar Flexion/Gastrocnemius |
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X |
| Ankle Eversion |
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X |
| Ankle Inversion |
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X |
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| Name of Scale and Number of Units |
MRC Scale - Extended
11 point scale
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| Description of Scale |
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(5-) Barely detectable weakness
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(4S) Same as 4 but stronger than reference muscle
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(4) Muscle is weak but moves the joint against a combination of gravity
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(4W) Same as 4 but weaker than reference muscle
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(3+) The muscle is capable of transient resistance but collapses abruptly. This degree of weakness is difficult to put into words, but it is a muscle which is able to move the joint against gravity and an additional small amount of resistance. it is not to be used for muscles capable of sustained resistance throughout the whole range of movement
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(3) Muscle cannot move against resistance but moves the joint fully against gravity With the exception of knee extensors,a the joint must be moved through the full mechanical range against gravity. If a patient has contractures that limit movement of the joint, the mechanical range will obviously be to the point at which the contractures cause a significant resistance to the movement. ’In the case of the knee extensors, the patient is graded 3 if the knee can be straightened to within 10” of full extension
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(3-) Muscle moves the joint against gravity but not through the full extent of the mechanical range of the joint
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(2) Muscle moves the joint when gravity is eliminated
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(1) A flicker of movement is seen or felt in the muscle
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Reference 1
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| Reference Details |
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Brooke,M.H.; Griggs,R.C.; Mendell,J.R.; et al (1981) Clinical trial in Duchenne dystrophy. I. The design of the protocol, Muscle and Nerve, Vol 4, pp 186 - 197
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| Other Information |
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This is the key reference for this version of MMT and gives the details of muscle testing positions.
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Reference 2
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| Reference Details |
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Muscle Study Group (2001) Randomized pilot trial of INF1a (Avonex) in patients with inclusion body myositis, Neurology, Vol 57, pp 1566 - 1570
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Reference 3
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| Reference Details |
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Muscle Study Group (2004) Randomised pilot trial of betaINF-1a in patients with inclusion body myositis, Neurology, Vol 63, pp 718 - 720
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