Grip Test (Grip Test)
Click the buttons provided below to view information contained in a specific part of this record:
|
General Information
|
| Objectives |
|
The forearm ischemic exercise test is one of the clinical tools which is commonly used for the detection of some muscle metabolic disorders. This clinical test generally consists in performing a grip exercise under ischemic conditions associated with regular blood sampling for biochemical analyses. Forearm ischemic exercise test presents many drawbacks.
The Grip Test is a non ischemic test for the evaluation of lactate and ammonia production following a standardized contraction. Since it is not ischemic and short, the Grip Test can be performed in safe conditions and provides an efficient screening test in muscle diseases with abnormal energy metabolism. Moreover, it can be used for the follow-up of patients.
The Grip Test is composed of a MIE analog grip handle and a devoted software (Institut de Myologie) managing the test, the patient database and the reports.
|
|
| Category of Outcome Measure |
Pathology
Impairment
Functional
|
|
| Chronology of Development |
|
1998: following the ischemic forearm exercise test stop due to deleterious effects in several patients, it was decided to design a new test which should be non-ischemic.
1999: after many tests for the protocole parameter tuning, the definitive Grip Test has be set up.
2003: first use in a clinical protocol aiming to assess the lactate metabolism in HAART treated and naive HIV-infected patients.
2006: use in MyoTox : prospective, pilot study evaluating the impact of nucleosidic analogues withdrawal in HIV infected patients presenting a myopathic syndrom under antiretroviral treatment.
2007: pathophysiological protocol on the Glycogenosis type III (15 patients).
2009: detection of a new glycogenosis defect (phosphoglucomutase 1 deficiency).
2009: about 1000 patients have underwent the Grip Test
|
|
| Mode of Assessment |
Administered by trained evaluator
|
|
| Age Group |
Adolescents (12 to 15 Years)
Adults (16 Years and Over)
chidren from 5
|
|
| Age Related Limitations |
|
Must be able to understand what is a maximal exercise.
|
|
| Languages |
| |
Original |
Definitive Validated Translation |
Informal Translation |
| English UK |
|
X |
|
| English US |
|
X |
|
| French |
|
X |
|
|
|
| Conditions of Use and Contact Information |
| Conditions of Use |
Payment of Academic/Non Profit Research Fee
|
|
| Copyright Owner |
|
Institut de Myologie for the software
|
|
| Postal Address |
|
GH Pitié-Salpêtrière, Bâtiment Babinski, 47/83 Bd de l'Hôpital
|
|
| Email Address |
|
jy.hogrel @ institut-myologie.org
|
|
|
|
|
Quantitative Muscle Testing
|
| Total Number of Muscles Tested (Bilateral) |
|
| Total Number of Muscles Tested (Unilateral) |
|
| Actual Muscles Tested |
| |
Proximal |
Distal |
Not Defined |
| Hand Grip |
|
X |
|
|
|
|
|
|
Device
|
| Description |
|
Analog grip handle (full scale: 100 daN; precision: 0.1% FSO)
|
|
| Purpose/Use |
|
The handle is used with a specific software for the managment of the Grip Test for the assessment of grip strength.
|
|
| Address |
|
6 Mortley Moor Road; Leeds LS124JF; UK
|
|
| Instruction Manual Availability |
An instruction manual is available
|
|
|
|
|
Reference 1
|
| Reference Details |
|
Hogrel J-Y, Laforêt P, Ben Yaou R, Chevrot M, Eymard B, Lombès A. A non-ischemic forearm exercise test for the screening of patients with exercise intolerance. Neurology, 56:1733-1738, 2001.
|
|
|
|
|
Reference 2
|
| Reference Details |
|
Ghosn J, Guiguet M, Jardel C, Benyaou R, Zeller V, Simon A, Valantin M-A, Amellal B, Assoumo L, Hogrel J-Y, Costagliola D, Katlama C, Lombès A. Muscle and liver lactate metabolism in HAART-treated and naive HIV-infected patients: the MITOVIR study. Antivir Ther, 10:543-550, 2005.
|
|
|
|
|
Reference 3
|
| Reference Details |
|
Stojkovic T, Vissing J, Petit F, Piraud M, Orngreen MC, Andersen G, Claeys KG, Wary C, Hogrel J-Y, Laforêt P. Muscle glycogenosis due to phosphoglucomutase 1 deficiency. N Engl J Med, 361:425-427, 2009.
|
|
|
|
